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While some individuals notice subtle appetite changes within 24 to 48 hours, many feel no significant difference initially

But sometimes it has the opposite effect

For example, if your original goal was to lose 30 pounds but youve stabilized at 25 pounds while building strength through resistance training, it might make sense to shift your focus to long-term health and maintaining your current progress

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More recently, dual incretin therapies such as tirzepatide have emerged that combine multiple metabolic pathways to enhance treatment outcomes