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Tirzepatide is a dual agonist that combines: GLP-1 (glucagon-like peptide-1) activity GIP (glucose-dependent insulinotropic polypeptide) activity This combination creates a stronger incretin effect, improving insulin sensitivity and appetite control more effectively than GLP-1 medications alone

However, this slower transit can be detrimental to your gut health and your microbiome (the community of microorganisms that live in and aid your digestive tract.) Decades of research have shown a significant link between slowed motility and harmful microbial overgrowths

2018;34(8):e3061

Standards of Care in Diabetes2023

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