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Candida-driven gut permeability allows bacterial lipopolysaccharides to activate thyroid antibody production, and mycotoxins impair the hepatic conversion of T4 to the active T3 form producing functional hypothyroid symptoms with or without abnormal TSH

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[23] Cardiovascular disease [edit] More recently, slightly elevated serum GGT has also been found to correlate with cardiovascular diseases and is under active investigation as a cardiovascular risk marker

doi:10.1056/NEJMoa2301972 PubMed: This landmark study demonstrated 24.2% mean weight loss at 48 weeks with the 12mg dose in 338 adults with obesity, establishing retatrutide as the most effective obesity medication tested to date

Some users store unmixed vials in the freezer for very long-term storage