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Insulin resistance drives androgen excess, which promotes abdominal fat storage, which worsens insulin resistance further

Measurable weight loss typically begins appearing around day 10 to 14, though individual response varies based on genetics, starting dose, and baseline metabolism

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This setup creates a controlled environment where you can work with confidence

When patients experience persistent gastrointestinal symptoms, general malaise and reduced well-being can diminish sexual desire, though this represents a secondary rather than direct pharmacological effect