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Surviving a greater number of pathogens has allowed these ancestral haplotypes to be inherited from generation to generation, but with the disadvantage that those older pathogens with which they have coexisted have also acquired resistance against them via co-evolution of their evasion mechanisms [171, 183]

Pantothenic Acid (B5) carrier of Coenzyme A, essential for Acetyl CoA and therefore energy production CoQ10 utilised as a carrier in complex II of ETC

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