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Notably, we detected a marked reduction in NRF2 expression in the lesioned skin of both clinical biopsy samples and the IMQ-induced psoriatic mouse model
The IVW method showed that the glutamate to pyruvate ratio and 3-carboxy-4-methyl-5-pentyl-2-furanpropanoate (3-CMPFP) played a significant mediating role in the causal effect of PNKP on migraine (P_value = 4.60 10 2 ), with a mediation effect value (1 2) of 0.02 (detailed data in Table S10)
Metformin in the diabetic brain: friend or foe
FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology vol
This unique glutamyl linkage distinguishes glutathione from typical peptides and contributes to its stability against common intracellular peptidases, which is important for both biological function and industrial handling
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