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The extract was then filtered twice by using the Whatman No

Intracellular pH determination Intracellular pH was determined using a pH-sensitive green fluorescent protein (pH-GFP) as previously described (Wang et al., 2019

The peptides are administered with a very fine needle, similar to what's used for insulin, just under the skin in the abdomen

Proinflammatory cytokines further stimulate ROS overproduction aggravating ARDS and lung damage causing a vicious circle between oxidative stress and cytokine storm

Numerous studies have confirmed that compromised autophagy and mitophagy are associated with ageing, leading to shortened lifespan in a wide range of ageing models, whereas restoration and enhancement of autophagy prolongs life and health in various animal species (Reference Aman, Schmauck-Medina and Hansen24, Reference Zimmermann, Madeo and Diwan26)

They are discussed for overlapping reasons, but they come from different biological concepts, are studied through different mechanisms, and raise different safety and regulatory questions