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Wanner C et al
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If a strong fishy odor is accompanied by cloudiness, sediment, color change, clumping, visible specks, or unexpected bubbles, the product should be discarded
Moreover, inflammation dysregulates neurotrophins such as BDNF and NGF, which are essential for neuronal growth and plasticity via TrkA/B/C and p75^NTR^ signaling pathways (Numakawa and Kajihara 2023
Lastly, the melancholic profile is based on eight items of waking up too early, quality of mood, hypophagia, decreased weight, linkage of mood to time of day (if worse in the morning), view of self, psychomotor agitation and psychomotor retardation (range 024)
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