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(Farr et al., 2019) found increased orbitofrontal cortex activation when controlling for BMI/weight changes
Immunohistochemistry with SOX10 (staining the cell nuclei of melanocytes) facilitates diagnosis of lentigo maligna, in this case showing an increased number of melanocytes along stratum basale of the skin, and nuclear pleomorphism
Giblin et al., 2026)
In addition, excessive androgen receptor activation alters transcriptional regulation of genes involved in glucose and lipid metabolism, thereby promoting hepatic steatosis and insulin resistance (72)
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