131 , e146353 (2021)
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Wegovy: weight-loss licence), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), exenatide
Circulating pigment epithelium-derived factor levels are associated with insulin resistance and decrease after weight loss
However, so far across studies with GLP1R agonists , cardiovascular measurements such as blood pressure have seen improvements in general, with no significant increases in adverse cardiovascular effects seen in patients even after 2 years (In fact, decreases were seen), suggesting that the cardiovascular benefits of decreased body weight may overcome any potential harm that increases in heart rate by GLP1R agonists may cause
Not to restrict, but to replenish