In research settings, this compound is often linked with reduction in stubborn fat deposits, particularly in the abdominal region
National Library of Medicine
That is the reality for a surprising number of researchers
However, as with any supplement, potential side effects and safety considerations exist, particularly for individuals with pre-existing health conditions
Of relevance, recent evidence indicates that SAM exerts anti-inflammatory effects by reducing the expression of the proinflammatory cytokine tumor necrosis factor-alpha (TNF) and increasing the expression of the anti-inflammatory cytokine interleukin 10 (IL-10)
The transfection assay clearly demonstrated a decrease in glutamine consumption due to reduced GLS1 levels, whereas this was not as apparent in the dendriplex PURE G4 -LA 12 -anti- GLS1 -siRNA assay