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[2] A deficiency of thyroid hormones can reduce basal metabolic rate up to 50%, while an excessive production of thyroid hormones can increase the basal metabolic rate by 100%

doi: 10.26355/eurrev_202011_23812 234 XieZShenPQuYXuJZhengCGaoYet al

Stages of life, lifestyle changes, diet and health conditions all impact the amount of vitamin B12 you need to avoid a deficiency