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The popularity of Wegovy (and off-label use of Ozempic for weight loss) skyrocketed, leading to periodic shortages of semaglutide products in 20222023 ( [14] )

Leveraging the University of California Health Data Warehouse enabled a realworld analysis of 6,871 patients with primary colon cancer and rigorous adjustment strategies to probe whether GLP1 RA exposure relates to fiveyear mortality. At the end of the study, researchers found that participants with colon cancer taking GLP-1 medications had a 15.5% mortality risk within 5 years, compared to 37.1% in participants not taking the drugs

But the peptide inside has fundamentally changed

Cancer Causes & Control

Bone broth contains amino acids and minerals that can interact with certain medications, such as blood thinners

So patients will be eligible for the bridge if they have a BMI of 35 or higher, a BMI of 30 or higher with uncontrolled hypertension, chronic kidney disease stage 3A or above, or heart failure with preserved ejection fraction