Biosensors 15:376 Roszkowski S, Durczynska Z (2025) Advantages and limitations of nanostructures for biomedical applications
It cites STEP 1, STEP 2 and STEP 3 for semaglutide and SURMOUNT 1-4 for tirzepatide as enrolling people across varying activity levels, with average weight loss of 5-10% without structured fitness
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Semaglutide, StatPearls Publishing, 2024
They discovered that semaglutide treatment improved body composition by reducing excess body fat, notably abdominal fat, and increasing the proportion of lean body mass, or weight that is not body fat
Diabetic dermopathy, necrobiosis lipoidica, or infections may occur independently of semaglutide use but require appropriate management