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Many men and women exercise regularly and eat healthy, but still struggle to reach their target weight

More serious potential adverse effects include pancreatitis, gallbladder disease (cholelithiasis, cholecystitis), acute kidney injury (especially with dehydration), and increased risk of hypoglycemia when used with insulin or sulfonylureas

Patients interested in retatrutide for any clinical reason would need to enrol in one of the active TRIUMPH Phase 3 trials through Eli Lilly's investigator network

Short to medium term use appears safe based on available evidence

Over time, this can lead to better overall health and reduced risk of obesity-related diseases such as heart disease, diabetes, and high blood pressure

Avoid Semaglutide-interacting drugs