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Toft-Nielsen MB, Damholt MB, Madsbad S, Hilsted LM, Hughes TE, Michelsen BK, et al

This is based on the observation that the livers of GCLM KO mice in all diet groups have high levels of active (phosphorylated) LKB1, a redox-sensitive kinase and the primary hepatic AMPK kinase 24

The NFS1 cysteine desulfurase can promote ironsulfur cluster biosynthesis

This conjugation renders the previously fat-soluble toxins completely water-soluble, allowing them to be safely flushed out of the body via bile and urine