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and once a method was validated, no changes were made to it
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Disadvantages: Because nasal absorption is highly dependent on mucosal health, airflow, and technique, the same dose may not yield consistent results from patient to patient, or even for the same patient on different days
iScience [Internet] 27(5):109784
Niemira BA
2001, AOD-9604 lost most of this fat-metabolism effect in mice that were genetically missing the beta-3 adrenergic receptor, suggesting that pathway carries part of the signal
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