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Mild side effects and potential risks, which should be referred to a doctor if they persist or worsen, include: pain, redness, or itching at the site of the injection mild diarrhea swelling sensation in the body More serious side effects, which require immediate medical attention, include: muscle cramps irregular heartbeat unusual weakness or tiredness swelling of the ankles or feet Severe reactions are very rare but require emergency intervention

Your doctor will usually perform assessments during your appointments to determine your need for future B12 shots

These symptoms typically resolve within 24 hours.* Not for Everyone: This therapy is not recommended for individuals allergic to cobalamin (B12), those with liver disease, or those currently taking medications that interact with methyl donors

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It is also contraindicated for epidural or spinal (intrathecal) injection procedures

Vitamin B12 (cobalamin) is an essential nutrient involved in energy metabolism, nerve function, and red blood cell production