Those with weight loss exhibited overall favorable shifts in measures related to cardiometabolic risk, Pickhardt adds, also noting that decreased muscle attenuation in patients who gained weight was consistent with a decrease in muscle quality
During the trial, additional anti-diabetic medication was initiated as an add on to randomized treatment by 2.4%, 1.1% and 2.8% of patients randomized to semaglutide tablets 7 mg, semaglutide tablets 14 mg and sitagliptin 100 mg, respectively
They also reported that the safety and tolerability of elecoglipron were similar to those of other GLP-1 medications at this stage of development
Increasing the dose over time ensures you receive the full benefits of semaglutide while reducing the likelihood of side effects like nausea or upset stomach
Liraglutide is generally well-tolerated
Buckley S, Scheele S, Kirk R, Knudsen L