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Non-Polar Molecules: Molecules with low polarity are more likely to cross the BBB because they can more easily dissolve in the lipid bilayer

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Ensure the detected value of the sample falls in the range of standard curve

Metab Brain Dis 20:275283 Rose C, Michalak A, Pannunzio P et al (1998) L-ornithine-L-aspartate in experimental portal-systemic encephalopathy: therapeutic efficacy and mechanism of action