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The oxidative stress induces an increase of membrane damage The extent of membrane damage was assessed by measuring the production of MDA, a widely recognized marker of lipoperoxidation whose production occurs in cells directly from a damage to the membrane structure and function

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Melanotan 2 is a synthetic analogue of -MSH (alpha-melanocyte stimulating hormone) , investigated in controlled laboratory settings for its interaction with melanocortin pathways related to pigmentation, metabolic signaling, and sexual response

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