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Kisspeptin, which has been used in trials to trigger ovulation, acts on the hypothalamic-pituitary-gonadal axis and can cause safe, physiologic LH surges for assisted reproduction
2.3 Cisplatin induces mitochondrial dysfunction When cisplatin enters the mitochondria, it acts directly on the inner mitochondrial membrane, leading to the impairment of the function of the electron transport chain, the reduction of ATP production and the induction of ROS generation (Elmorsy et al., 2024), and the inhibition of the efficient antioxidant defence system composed of glutathione (GSH) and enzymes, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx), in the interstitial space of the mitochondrial membrane
UK guidance advises caution in patients with a history of pancreatitis
Safety Profile BPC-157 does not have a clear safety profile in humans
Rheumatology (Oxford) (2010) 49(8):144760
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