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IGF-1 DES is a truncated version (des(1-3)IGF-1) that has higher potency at the receptor (~5-10x) but a very short half-life (~2030 minutes)
Because the vitamin is injected directly into the bloodstream, patients often feel results within hours to a few days
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The activated beta-3 receptor couples to stimulatory G-proteins (Gs), which activate the enzyme adenylyl cyclase
Peripheral artery diseaseoccurs when the peripheral arteries become clogged by plaque
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