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Hill suggests starting with approaches like food and exercise rather than supplements

273 In addition, in a rat model of inflammatory OA induced by monoiodoacetic acid (MIA), researchers have shown that the activation of GLP-1R triggers the PKA/CREB signaling pathway, leading to a reduction in cartilage inflammation

doi: 10.29252/beat-060205 205 El MessaoudiSSchreuderTHKengenRDRongenGAVan Den BroekPHThijssenDHJet al

These findings strongly suggest that LAC deficits contribute to a depression-like state in mice, leading the scientists to wonder whether the molecule plays a similar role in humans

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