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The key point is that the pancreas falls clinical victim while liver injury is generally silent - but why

10.1016/j.bbrc.2018.12.149 45 LiS.-L.WangZ.-M.XuC.CheF.-H.HuX.-F.CaoR.et al (2022)

Semaglutide also has a longer half-life than the older GLP-1s and may have a stronger effect on receptors in the brain, which could help explain the difference in findings, Moreno adds

The key to deciding when to increase your dose is tolerability, not immediate results

So, by delaying its breakdown, GLP-1 stays in your body longer, helping lower blood sugar levels

The needles are very small, and most people describe it as less painful than a finger prick for blood sugar testing