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The results showed that maternal RPM supplementation in late gestation promoted more significant global DNA methylation in the offsprings liver, accompanied by a general alteration in the hepatic transcriptome, proteome, and metabolome, favoring the enrichment in glucose and lipid metabolism, glutathione, and immune system pathways (Palombo et al., 2021)

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Indeed, cAMP levels can be elicited by GLP-1 treatment of mouse cardiomyocytes without increasing intracellular Ca 2+ or inducing contractility [38]

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