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While all three medications can support weight loss and improve blood sugar control, each has unique features worth considering

17 Both the lipid-soluble GLP-1RAs and small-molecule SGLT-2is were considered to be able to cross the BBB in numerous preclinical trials

Gastrointestinal Complications: Although generally manageable, patients should be advised about common side effects like nausea and diarrhea

And we dont ultimately know, but he emphasized in his paper, it was written with somebody else in his group that there are a number of downsides of long-term calorie restriction