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Usp9x contributes to the development of sepsis-induced acute kidney injury by promoting inflammation and apoptosis in renal tubular epithelial cells via activation of the TLR4/nf-b pathway

thereby, p53 may target pro-apoptotic genes and promote their expression

For silencing FOXO4, specific small interfering RNA (siRNA) was employed, with a negative control siRNA, and transfection was conducted using Lipofectamine 3000 [2]

Complanatoside A targeting NOX4 blocks renal fibrosis in diabetic mice by suppressing NLRP3 inflammasome activation and autophagy

The most important characteristic of the assay is direct visualization of the GST activity by the naked eye, which makes it more convenient than other methods that rely on advanced instrumentation