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These techniques, even though they offer the possibility of obtaining a high-resolution visualization of synaptic transmission elements, also suffer from limitations such as a narrow depth of field (1.2 mm) (Dunn and Sutton, 2008

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doi: 10.1038/s41557-020-0465-9 232 ReddyK.ZamiriB.StanleyS

Meta-analyses find it improves cognition in mild cognitive impairment and early Alzheimers, with one review putting the benefit at roughly four to twelve weeks per course, longer than a nootropics washout and shorter than a durable structural change, and it usually needs maintenance

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Both injection types are far more effective at raising B12 levels than oral supplements, but the best method really depends on your individual needs