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Important precautions with GLP-1 receptor agonists include: Patients also taking insulin or sulfonylureas are at increased risk of hypoglycaemia

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A previous study has shown that the combination of GLP-1R agonist and angiotensin receptor blocker (ARB) increases natriuresis compared to GLP-1R agonist alone in Otsuka LongEvans Tokushima Fatty rats, a model of obese type 2 diabetes [68]