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For studies with a calorie-restricted and body-weight-loss-matched control group, HFHS diet (58 kcal% fat, D12331i, Research Diets) was weighed and provided as one separate pellet per mouse at the time of injection
The Cleveland Clinics long-term data showed: Over 10 years, surgical patients lost on average 21.6% of their TBW versus only 6.8 % lost by GLP-1 users
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