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La Agencia de Medicamentos y Alimentos de Estados Unidos, la FDA, aprob la semaglutida en 2017 para mejorar el control de los niveles del azcar en sangre en adultos con diabetes tipo 2 y, aos ms tarde, en junio de 2021, para el tratamiento de obesidad o sobrepeso en personas con factores de riesgo relacionados, como presin arterial alta o diabetes
doi: 10.1186/s12986-022-00685-1 25 LouisPDuncanSSheridanPWalkerAFlintH
Detailed reviews of mechanisms linked with cardiorenal protection have been published elsewhere
Whether this mechanism translates into greater weight loss than dual-agonist therapies remains a hypothesis no head-to-head clinical trials have yet been conducted
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GI side effects are common to both compounds but may be more pronounced with retatrutide
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