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Ozempic helps with weight loss through its action as a GLP-1 receptor agonist, which mimics the effects of the natural hormone GLP-1 in the body

Besides, M1 macrophage markers expression, CCR7, TNF- an IL-6 was lowered

Specifically, it acts as an agonist (activator) for the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor

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Patients in the UK seeking weight management support should consult their GP or an NHS specialist obesity service, where NICE-recommended options such as semaglutide (Wegovy) and tirzepatide (Zepbound) are currently available

The results highlight that GLP-1 RA treatment was consistently linked to reductions in PASI scores and, in most cases, improvements in DLQI