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View Study [3]"IGF-I and IGFBP-3 transport in the rat heart" Boes M, Dake BL, et al., 2003 Finding: This study showed that LR3 IGF-I can bypass IGF binding proteins that normally sequester IGF-1, demonstrating why LR3 has greater bioactivityit reaches target tissues more effectively than native IGF-1

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A second family, BPC-157 and TB-500, targets tissue repair rather than the GH axis: BPC-157 is proposed to work through angiogenesis, nitric-oxide signaling, and anti-inflammatory activity, while TB-500 binds actin to promote cell migration, blood-vessel formation, and collagen deposition

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Ullah H et al