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The mechanisms behind the benefits of metabolic surgery are still being investigated

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For example, scientists are developing GLP-1 drugs that require only monthly injections

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Effects of tesamorelin, a growth hormone-releasing factor, in HIV-infected patients with abdominal fat accumulation: a randomized placebo-controlled trial with a safety extension

Several factors, such as diet, microbial metabolism of tryptophan, and endogenous enzymatic activity, can provide critical signals to the host, aiding in resisting colonization and defending against mucosal inflammation [51]