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A study that compared 24 obese patients with MC-4R deficiency to 80 healthy controls (40 obese and 40 lean) found that those with MC-4R mutations consumed significantly more high-fat meals
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Joint Pain and Inflammation: Users may suffer from joint discomfort, undermining physical performance
Experiments with human samples were approved by the Research Ethics Committee, the Wako Safety Center in RIKEN (approval number: Wako3 30-4(2))
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