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Because of this risk, people with a personal or family history of medullary thyroid carcinoma (MTC) or those who have Multiple Endocrine Neoplasia syndrome Type 2 (MEN 2) should not use these GLP-1 medications

A notable subset of patients with MCAS or specific genetic variants (such as CBS gene mutations) have impaired transsulfuration pathways or severe sulfur sensitivities

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