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Unlike many experimental NRF2 activators (e.g., synthetic electrophiles or natural compounds like sulforaphane), DMF has undergone extensive Phase III trials, demonstrating its efficacy and safety in humans

Chen Z, Hu T, Zhu S, Mukaisho K, El-Rifai W, Peng DF

International journal of sport nutrition and exercise metabolism, 25(5), 417-426

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And people talk all the time about high intensity interval training