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He et al., 2017

Front NeuroSci

Some have proposed that ammonia is converted to glutamine, which causes cerebral edema either directly by its osmotic effect 37,38 or indirectly by decreasing other osmolytes, thereby promoting water retention

A phase 2 clinical trial showed that retatrutide treatment for 48 weeks led to significant body weight loss in obese patients (NCT04881760)

Compound Overview Class of Compound: Peptide Mechanism of Action: Semaglutide is a synthetic version of glucagon-like peptide-1 (GLP-1) and thus mimics the action of this human incretin

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