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DES(1-3) IGF-1 is a truncated variant missing the first three N-terminal amino acids (Gly-Pro-Glu), which also reduces IGFBP binding but through a different structural mechanism removal of the N-terminal tripeptide rather than charge substitution

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Both matter, but they don't substitute for each other

Glutathione is a tripeptide made up of three essential amino acids, including cysteine, glycine, and glutamic acid

Abstract Background Patients on dialysis often suffer from carnitine deficiency due to reduced intake, reduced synthesis in the kidneys, and clearing through dialysis