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Stress and poor sleep do not directly lower levels, but they increase nutrient demand and can worsen symptoms of existing deficiencies

Aboubakr M, Elshafae SM, Abdelhiee EY, Fadl SE, Soliman A, Abdelkader A, Abdel-Daim MM, Bayoumi KA, Baty RS, Elgendy E, Elalfy A, Baioumy B, Ibrahim SF, Abdeen A (2021) Antioxidant and Anti-Inflammatory Potential of Thymoquinone and Lycopene Mitigate the Chlorpyrifos-Induced Toxic Neuropathy

doi: 10.3389/fimmu.2024.1429836, 79

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et al., PNAS (2013) Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

This includes activities like exercise or sports