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Telomerase activation creates an unresolved carcinogenicity question

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Among a small subgroup of participants who smoked cigarettes at baseline, those treated with semaglutide had significantly greater reductions in average cigarettes per day compared to those in the placebo group, suggesting that semaglutide might reduce both alcohol and nicotine use

That said, because vitiligo involves melanocyte function and glutathione affects melanin production pathways, it is a reasonable precaution for anyone with a personal or family history of vitiligo or other autoimmune skin conditions to consult a dermatologist before starting supplementation

Most compounded semaglutide tolerates up to 8 hours at room temperature without measurable potency loss, based on stability testing for the semaglutide molecule