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All efficacy end points were analyzed in the full analysis population (all the participants who underwent randomization, in accordance with the intention-to-treat principle), and safety end points in the safety analysis population (all the participants who underwent randomization and received 1 dose of an active drug or placebo)

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Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease

American Sleep Disorders Association and Sleep Research Society