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Methylene blue is excreted in urine and bile
Biosynthesis and role of the endothelium-derived vasodilator, nitric oxide in gastric mucosa
The constipation pathway involves slowed colonic transit
Care is taken to make the injection as comfortable as possible
Therefore, some clients may need more frequent injections due to increased vitamin B12 utilization or loss
Higher-dose oral B12 (e.g., 1000 g daily) is sometimes used but should only be considered under clinical supervision with appropriate monitoring, particularly in cases of malabsorption where intramuscular treatment remains the first-line approach in UK practice
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