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Kitzman DW, Brubaker P, Morgan T, Haykowsky M, Hundley G, Kraus WE, et al
Circadian regulation of glutathione levels and biosynthesis in Drosophila melanogaster
This catabolic state leads to anabolic resistance, tipping the balance between protein synthesis and degradation towards net catabolism in critically ill patients (67,68)
Studies on GSTO1-1 also suggested a protective effect of this enzyme on PD, exerted through the inhibition of the active form of interleukin-1 (IL-1 ) which is a critical factor in inflammatory response 47,58
doi: 10.1007/s12603-009-0084-z 49 BaumgartnerRNWayneSJWatersDLJanssenIGallagherDMorleyJE
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