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This may involve: Adjusting Medication Lowering the baclofen dose under medical supervision Switching to alternative muscle relaxants if appropriate Monitoring for improvement of urinary symptoms Supportive Measures Timed voiding techniques to encourage regular bladder emptying Use of catheterization in severe cases to relieve bladder pressure Hydration management to avoid concentrated urine that can irritate the bladder When to Consider Specialist Care If urinary retention persists despite adjustments, referral to a urologist or neurologist may be necessary

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An intact BBB has very low paracellular permeability and high trans-endothelial electrical resistance (TEER)

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