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The study follows a cautious, stepwise dose-escalation approach: starting from the maximum recommended starting dose and moving upward only after a thorough safety review at each level

Eat smaller, more frequent meals rather than large portions, avoid high-fat and greasy foods that delay gastric emptying further, eat slowly and mindfully to recognize satiety signals, stay well-hydrated with 8-10 glasses of water daily, and identify individual trigger foods through a food diary

For estimation of the telomerase activity, the procedure outlined in (Al-dulaimi et al 2024) was followed

2003 Oct;56(5):270-4

A low glycemic load denotes a smaller expected postprandial glucose elevation than a high glycemic load (Bhupathiraju 2014

Gene expression analysis Total RNA from the hypothalamus or interscapular BAT was extracted with TRIzol reagent (Invitrogen)