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Clinical data shows MOTS-c improves insulin sensitivity by 3040%, while 5-Amino-1MQ increases energy expenditure by 9% in preclinical modelscombined effects exceed monotherapy outcomes

It stimulates lipolysis and inhibits lipogenesis through beta-3 adrenergic receptor upregulation without the growth-promoting effects of full hGH

doi: 10.1159/000053183

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