Although GLP-1RAs confer anti-inflammatory and glycemic benefits, persistent reductions in nutrient inflow and delayed gastric emptying may limit the availability of amino acids and micronutrients required for tissue maintenance and redox homeostasis
It also mimics the effect of another class of hormones called glucose-dependent insulinotropic polypeptide (GIP)
The authors also emphasized that the wider use of these drugs should consider social and commercial determinants of health, including access, affordability and insurance coverage, to avoid deepening existing health inequities among people living with obesity
Novo Nordisk has not yet reported a subgroup analysis for these patients, but such an analysis could offer useful insights into whether GLP-1RAs confer cognitive advantage in this subgroup
While the thigh can be a good choice for many, there are a few things to keep in mind to reduce discomfort: Avoid the Muscle : One concern with thigh injections is accidentally injecting too deep and hitting the muscle
Weight loss injections like Wegovy (semaglutide), Zepbound (tirzepatide), and Mounjaro are clinically proven and effective medications