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PMID: 41880199 Uaktrk E et al

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Real-world use often extends beyond this timeframe, particularly for individuals with significant obesity or metabolic dysfunction

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These laxatives, often used for prolonged periods to treat constipation, disrupt the normal processes of colonic mucosal cells, leading to the accumulation of pigment within macrophages

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Starting them at the same time makes it harder to identify which medication is causing any problems

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Se debe tener cuidado cuando se utiliza junto con suplementos de cobre o tratamientos que afecten el metabolismo del cobre

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A protocol that requires clinic visits or self-injection to sustain is one that tends to lapse, and a lapsed protocol produces limited long-term results

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